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New study tests MRI as a safer way to find brown fat

NCT ID NCT02237872

Diagnosis Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether MRI can detect brown adipose tissue (brown fat) as accurately as PET scans, which use a radioactive tracer. Eight healthy adults had both scans under mild cold conditions. The goal is to see if MRI, which avoids radiation, could replace PET for brown fat detection in future obesity research.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If MRI proves accurate, it could offer a safer, radiation-free way to detect brown fat, which may help in obesity research.
What could go wrong
This is a tiny pilot study with only 8 people, so results may not apply widely. MRI might not match PET's accuracy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

8 people

The number who actually took part.

Started

Jan 2015

Finished

Aug 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy adult human with a BMI \<28

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Each subject must be fully informed and have signed consent. * BMI \< 34 * Normal neurological and psychological development / able to give consent * Willingness to participate in this study Exclusion Criteria: * Subjects less than 18 years of age * Severe claustrophobia * Women who are pregnant, nursing an infant or planning to become pregnant in the next 30 days * People who have a condition that makes MRI unsafe for them (for example, cardiac pacemaker, epicardial pacemaker leads, cochlear implants, metal aneurysm clip, iron filings in your eyes or metal halo devices) * Have had radiation therapy or chemotherapy in the 2 months prior to PET scan * Subjects are taking medications that may interfere with BAT detection

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brown adipose tissue Obesity

Contacts and locations

Locations

  • Biomedical Research Imaging Center

    Chapel Hill, North Carolina, 27599-7513, United States

  • Biomedical Research Imaging Center

    Chapel Hill, North Carolina, 27599, United States

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