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Brain scan breakthrough: new MRI method could spot autism in kids

NCT ID NCT02165410

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This study tested whether a special MRI technique called ASL-MRI can measure blood flow in the brains of children with autism. The goal was to see if this could be used as a non-invasive diagnostic tool, similar to PET scans but without radiation. Researchers studied 115 children aged 5 to 17 with autism or suspected autism, comparing MRI results with other methods like eye tracking.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a non-invasive MRI-based method to help diagnose autism in children.
What could go wrong
This is an early-stage observational study, not a treatment trial. The results may not translate into a reliable diagnostic test for all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

115 people

The number who actually took part.

Started

Nov 2013

Finished

Sep 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 months to 18 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patient diagnosed autist or suspected autist : males and females with the diagnosis of autism based on the following criteria: * 5 years ≤ age \< 18 years, * demand for MRI in the etiologic assessment (suspected autism) or MRI control in the treatment (diagnosed with autism) * obtaining written consent from parents or legal guardians of patients. Patients diagnosed with mental retardation or suspected with mental retardation : males and females with the diagnosis of mental retardation using the following criteria: * 5 years ≤ age \< 18 years, * demand for MRI in the etiologic assessment (suspected mental retardation) or MRI control in the treatment (diagnosed with mental retardation) * obtaining written consent from parents or legal guardians of patients. Healthy control subjects: males and females: * 5 years ≤ age \< 18 years * no known neurological or psychiatric disorder obtaining written consent with parents or legal guardians of volunteers. Very young patients suspected of autism: male and female with suspected autism 1. 18 months ≤ age \<5 years 2. demand of MRI in the etiologic assessment 3. obtaining written consent from parents or legal guardians. Very young patients suspected of mental retardation : male and female with suspected mental retardation 1. 18 months ≤ age \<5 years 2. demand of MRI in the etiologic assessment 3. obtaining written consent from parents or legal guardians. All subjects must be registered with the social security. Exclusion Criteria: For all subjects: * Indication against performing MRI (pacemaker, an implanted metal foreign body, claustrophobia), * Inability of healthy volunteers to remain still during the MRI examination. Healthy control subjects: males and females: * aged between 5 years and 18 years * no known neurological or psychiatric disorder * obtaining written consent with parents or legal guardians of volunteers. All subjects must be registered with the social security. Exclusion Criteria: For all subjects: * Indication against performing MRI (pacemaker, an implanted metal foreign body, claustrophobia), * Inability of healthy volunteers to remain still during the MRI examination.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades Service de Radiologie Pédiatrique

    Paris, 75743, France

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Other studies related to the condition(s) this trial covers.