Brain scan breakthrough: new MRI method could spot autism in kids
NCT ID NCT02165410
First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 1 time
Summary
This study tested whether a special MRI technique called ASL-MRI can measure blood flow in the brains of children with autism. The goal was to see if this could be used as a non-invasive diagnostic tool, similar to PET scans but without radiation. Researchers studied 115 children aged 5 to 17 with autism or suspected autism, comparing MRI results with other methods like eye tracking.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a non-invasive MRI-based method to help diagnose autism in children.
- What could go wrong
- This is an early-stage observational study, not a treatment trial. The results may not translate into a reliable diagnostic test for all cases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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115 people
The number who actually took part.
- Started
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Nov 2013
- Finished
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Sep 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 months to 18 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patient diagnosed autist or suspected autist : males and females with the diagnosis of autism based on the following criteria: * 5 years ≤ age \< 18 years, * demand for MRI in the etiologic assessment (suspected autism) or MRI control in the treatment (diagnosed with autism) * obtaining written consent from parents or legal guardians of patients. Patients diagnosed with mental retardation or suspected with mental retardation : males and females with the diagnosis of mental retardation using the following criteria: * 5 years ≤ age \< 18 years, * demand for MRI in the etiologic assessment (suspected mental retardation) or MRI control in the treatment (diagnosed with mental retardation) * obtaining written consent from parents or legal guardians of patients. Healthy control subjects: males and females: * 5 years ≤ age \< 18 years * no known neurological or psychiatric disorder obtaining written consent with parents or legal guardians of volunteers. Very young patients suspected of autism: male and female with suspected autism 1. 18 months ≤ age \<5 years 2. demand of MRI in the etiologic assessment 3. obtaining written consent from parents or legal guardians. Very young patients suspected of mental retardation : male and female with suspected mental retardation 1. 18 months ≤ age \<5 years 2. demand of MRI in the etiologic assessment 3. obtaining written consent from parents or legal guardians. All subjects must be registered with the social security. Exclusion Criteria: For all subjects: * Indication against performing MRI (pacemaker, an implanted metal foreign body, claustrophobia), * Inability of healthy volunteers to remain still during the MRI examination. Healthy control subjects: males and females: * aged between 5 years and 18 years * no known neurological or psychiatric disorder * obtaining written consent with parents or legal guardians of volunteers. All subjects must be registered with the social security. Exclusion Criteria: For all subjects: * Indication against performing MRI (pacemaker, an implanted metal foreign body, claustrophobia), * Inability of healthy volunteers to remain still during the MRI examination.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Necker-Enfants Malades Service de Radiologie Pédiatrique
Paris, 75743, France
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Other studies related to the condition(s) this trial covers.
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