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New MRI-Guided radiation aims to cut prostate cancer treatment time

NCT ID NCT05676463

First seen Mar 11, 2026 · Last updated Jun 22, 2026 · Updated 14 times

Summary

This phase 2 trial tested whether MRI-guided radiation therapy, given in fewer but higher doses, could safely treat high-risk prostate cancer while reducing side effects. The study enrolled 6 men with localized, high-risk prostate cancer who also received standard hormone therapy. The goal was to see if this approach could shorten overall treatment time compared to standard radiation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MRI-guided radiation therapy and antiandrogen therapy

What this could lead to

If successful, this approach could offer a shorter, more precise radiation treatment for high-risk prostate cancer with fewer side effects.

What could go wrong

This was a small, terminated phase 2 trial with only 6 participants, so results are very preliminary and may not apply to larger groups. The treatment still requires ongoing hormone therapy.

Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.