New MRI method could spot oral cancer early in rare disease patients
NCT ID NCT07649031
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study explores whether MRI scans can safely and accurately detect cancerous or precancerous mouth lesions in people with Fanconi Anemia, a rare genetic condition that raises cancer risk. Researchers will compare MRI results to standard biopsies in 80 adult participants. If successful, this non-invasive approach could reduce the need for painful tissue sampling and allow earlier detection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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May 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with Fanconi anemia
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with a diagnosis of Fanconi Anemia who are willing to participate and willing to have MRIs * Willing to provide informed consent Exclusion Criteria: * Patient without diagnosis of FA * Patients with FA who are under the age of 18 * Unable to tolerate any MRI due to claustrophobia * Any contraindication for the MRI * Unable to provide informed consent or comply with the study protocol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a single drink reveal how alcohol triggers oral cancer?
- Gene therapy aims to fix bone marrow failure in fanconi anemia
- New transplant method aims to reduce complications in bone marrow failure patients
- New hope for rare cancer: targeted drug afatinib tested in fanconi anemia patients
- New drug combo aims to make bone marrow transplants safer for kids