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Can a new MRI shortcut cut scan time without sacrificing quality?

NCT ID NCT04907487

Knowledge-focused Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a technique called compressed sensing can speed up a specific type of brain MRI (QSM) without losing image quality. 82 people, including some with multiple sclerosis, had extra scan sequences added to their routine MRI. The goal was to see if the faster scans produce the same signal as the standard ones.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could make brain MRI scans faster and more comfortable for patients while maintaining image quality.
What could go wrong
This is a small, completed technical study focused on image quality, not on treating any disease. The results may not apply to all MRI machines or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

82 people

The number who actually took part.

Started

Dec 2021

Finished

May 2025

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Two groups of patients will be included as part of this research protocol: * Group I: Patients with MS * Group II: Patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS pathology, age and gender matched with group I.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For patients with MS: * Patient over 18 years old * Presenting MS defined according to McDonald's revised criteria for spatial and temporal clinical or radiological dissemination \[16\], * Should benefit as part of the care of an MRI examination with or without injection of gadolinium * Express consent to participate in the study * Affiliate or beneficiary of a social security scheme For patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS disease: * Patient over 18 years old * Should benefit as part of the care of an MRI examination with or without injection of gadolinium * Express consent to participate in the study * Affiliate or beneficiary of a social security scheme Exclusion Criteria: * For patients with MS: * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman For patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS disease: * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman * Patient with inflammatory and / or demyelinating pathology of the CNS Secondary exclusion criteria : * Motion artefact not allowing interpretation of images * Patient who did not perform one of the following sequences: 3D T1 TFE, 3D FLAIR (for MS patients), SWI QSM 1.0iso 8 echoes. Secondarily excluded patients will be replaced.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MRI

Contacts and locations

Locations

  • Hhopital fondation adolphe de rothschild

    Paris, Paris, 75019, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.