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MRI reveals hidden jaw disc tears in 282 patients

NCT ID NCT07298512

Knowledge-focused Sponsor: Recep Tayyip Erdogan University Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether MRI scans can reliably find a torn disc in the jaw joint (temporomandibular joint). Researchers reviewed MRI images and medical records from 282 people to see how often disc tears occur and how they relate to pain, disc shape, and bone changes. The goal was to better understand how MRI can help diagnose this condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

282 people

The number who actually took part.

Started

Nov 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of approximately 282 patients (200 females and 82 males) aged 14-79 years who have undergone TMJ MRI scans for clinical evaluation. Patients will be included if they have complete MRI images (open- and closed-mouth) and corresponding clinical records, including Visual Analogue Scale (VAS) pain scores and detailed dental status. Individuals with systemic disorders affecting bone metabolism, history of bone-altering medications, current orthodontic treatment, prior head or neck trauma or surgery, head or neck cystic or tumoral pathology, previous radiotherapy or chemotherapy, pregnancy, or presence of ferromagnetic objects in the head will be excluded. The population will be stratified into two cohorts based on the presence or absence of TMJ disc perforation as determined by MRI.

Ages

14 to 79 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with available temporomandibular joint (TMJ) MRI scans (both open- and closed-mouth) * Age ≥14 years * Complete clinical records including Visual Analogue Scale (VAS) pain scores and dental status * Willingness to participate in the study and provide informed consent (for prospective studies) Exclusion Criteria: * Presence of systemic disorders affecting bone metabolism, including rheumatoid arthritis, chronic systemic corticosteroid therapy, Paget's disease, hypo- or hyperparathyroidism, osteomalacia, or renal osteodystrophy * History of medications that could alter bone architecture * Current orthodontic treatment * History of head and neck trauma or surgery * Presence of head and neck cystic or tumoral pathology * Prior radiotherapy or chemotherapy * Pregnancy * Presence of ferromagnetic objects in the head (contraindication to MRI)

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Conditions

The condition(s) this trial relates to.

bone marrow disorder temporomandibular joint dysfunction syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone marrow Magnetic resonance imaging Temporomandibular joint disc displacement

Contacts and locations

Locations

  • Recep Tayyip Erdoğan University Faculty of Dentistry

    Rize, Turkey (Türkiye)

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