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New MRI technique may spot brain tumor recurrence without a biopsy

NCT ID NCT04373720

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 33 times

Summary

This study tests whether magnetic resonance elastography (MRE), a special MRI that measures tissue stiffness, can tell the difference between radiation necrosis (scarring from radiation) and recurrent glioma (tumor regrowth) in people who have already been treated for brain cancer. About 80 adults with a history of glioma will undergo MRE and standard MRI. The goal is to see if stiffness measurements can accurately distinguish the two conditions, which could lead to better diagnosis and treatment decisions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a non-invasive way to distinguish between tumor regrowth and radiation damage, helping doctors choose the right treatment without unnecessary surgery.

What could go wrong

This is a small early-stage study, so results may not apply to all patients. The technique may not reliably tell the difference in all cases, and further research will be needed.

Conditions

The condition(s) this trial relates to.

glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.