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New MRI technique could replace biopsy for brain tumor grading

NCT ID NCT06916715

Diagnosis Sponsor: Shengjing Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether magnetic resonance elastography (MRE), a special type of MRI that measures tissue stiffness, can accurately determine the grade of brain tumors without needing a surgical biopsy. Researchers reviewed data from 626 brain tumor patients to see how well MRE works compared to standard tissue analysis. The goal is to provide a safer, non-invasive way to assess brain tumors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

626 people

The number who actually took part.

Started

May 2017

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This retrospective study enrolled 626 patients diagnosed with intracranial space-occupying lesions who underwent magnetic resonance elastography (MRE) at Shengjing Hospital between May 2017 and September 2025. All participants had available MRE data, met inclusion criteria (scheduled for intracranial space-occupying lesion resection surgery and provided written informed consent), and covered diverse intracranial space-occupying lesions , serving as the cohort for MRE-based space-occupying lesions characteristic analysis.

Ages

7 to 83 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Tumor diameter \> 2 cm * MR elastography performed within one week before surgery Patients were excluded if they had: * incomplete MRI or MRE data * A history of brain trauma, brain tumors, or surgery * Received chemotherapy, radiotherapy, or hormone therapy for any reason before surgery * Tumors that could not be assigned grades according to the fifth edition of the WHO Classification of CNS (WHO CNS5) * MRE examinations with suboptimal wave image quality (e.g., motion artifacts or inadequate wave amplitude)

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Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain neoplasms

Contacts and locations

Locations

  • Shengjing Hospital

    Shenyang, Liaoning, 110000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.