Artery size may predict cancer spread in rectal cancer patients
NCT ID NCT07419516
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 690 rectal cancer patients to see if the size of a specific artery (the middle rectal artery) on MRI scans could help predict whether cancer has spread to nearby lymph nodes. The goal was to create a tool that helps doctors decide if more extensive surgery is needed. The study found that certain imaging features, including artery diameter, were linked to lymph node spread, which could improve surgical planning.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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690 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This retrospective cohort study included adult patients (aged 18-75 years) with pathologically confirmed rectal adenocarcinoma located below the peritoneal reflection, who had complete preoperative pelvic MRI data and were treated at The First Affiliated Hospital of Fujian Medical University between 2022 and 2024. The study aimed to analyze this population to identify risk factors and develop a predictive model for clinically suspected lateral lymph node metastasis.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age at diagnosis between 18 and 75 years * Pathological confirmation of rectal adenocarcinoma by endoscopic biopsy * Imaging confirmation that the tumor was located below the peritoneal reflection * Availability of rectal MRI scans providing detailed imaging of the pelvic region * Received treatment at The First Affiliated Hospital of Fujian Medical University between January 2022 and December 2024 Exclusion Criteria: * Pathological diagnosis of non-primary rectal malignancies * Previous treatment for rectal cancer with chemotherapy, radiotherapy, or surgery, with the current presentation indicating recurrence * Incomplete rectal MRI data or poor image quality affecting interpretation * Incomplete medical or clinical records. Ultimately, 690 patients were included in the final analysis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, 350004, China
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