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New weight loss program targets PTSD-Related barriers in veterans

NCT ID NCT04563741

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a weight management program called MOVE!+UP, designed specifically for veterans with PTSD who are overweight or obese. The program adds extra support to standard PTSD care to help overcome barriers like stress and unhealthy habits. Researchers compared it to the standard VA weight program in 174 veterans to see if it leads to greater weight loss and improved PTSD symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioral weight management program (MOVE!+UP)
What this could lead to
If it works, this could offer a better weight loss approach for veterans with PTSD that also eases PTSD symptoms.
What could go wrong
This is a completed study with 174 participants, so results are limited in size and may not apply to all veterans. The program is behavioral, so individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

174 people

The number who actually took part.

Started

Oct 2020

Finished

Mar 2025

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * PTSD Diagnosis: standard criteria for PTSD Checklist for DSM-5 (PCL-5): lifetime experience of trauma and a score of 33 * Overweight or obesity based on Body Mass Index (BMI) of 25 kg/m2 * Primary Care Provider or other physician approval * Willing to participate in all intervention or control and assessment activities * Enrolled in PTSD treatment * Must have active VA Puget Sound Health Care System medical record. Exclusion Criteria: * Not fluent in English, severe hearing loss, no phone access * Current MOVE! participation * Current pregnancy * Based on clinical judgment, would be unable to participate because of: * acutely exacerbated substance use, mental health, or chronic medical conditions * or moderate to severe chronic, progressive neurologic conditions such as Dementia * had bariatric surgery within the last 12 months or plan to undergo bariatric surgery within the next 6 months. * Report they cannot safely weigh themselves using the mailed study scale due to mobility issues or use of assistive devices * Baseline weight \>440 lbs

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Overweight PTSD

Contacts and locations

Locations

  • VA Puget Sound Health Care System Seattle Division, Seattle, WA

    Seattle, Washington, 98108-1532, United States

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Other studies related to the condition(s) this trial covers.