Braces wearers: new study reveals best mouthwash for cleaner teeth
NCT ID NCT07490873
First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times
Summary
This study tests three different mouthwashes (chlorhexidine, cetylpyridinium chloride, and essential oil) in 24 people with braces to see which one reduces plaque and gum inflammation best. Participants will try each mouthwash for a week, with breaks in between. The goal is to find the most effective and patient-friendly option for keeping teeth and gums healthy during orthodontic treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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14 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 14-30 years. * Wearing orthometric-type fixed orthodontic appliances(metallic brackets and archwires) and currently in alignment stage. * Able and willing to attend all study visits and comply with study procedures, including washout periods and mouthwash use. * Baseline oral status after preparatory phase: plaque index (Löe \& Silness) ≥ 1.0 and gingival index (Löe \& Silness) ≥ 0.5. * BOP less than 10%. * Systemically healthy individuals with no history of antibiotic use or other medications in the preceding 3 months. * Willing to refrain from using any other mouthwash or antimicrobial oral hygiene product (except for the assigned study mouthwash and their routine toothpaste) throughout the study. * Provide written informed consent (and parental/guardian consent if under legal age). Exclusion Criteria: * Periodontitis patients and untreated caries requiring urgent care. * Smoking or use of tobacoo/nicotine products(including vaping). * Known allergy or hypersensitivity to CHX, CPC, EO components (thymol, eucalyptol, menthol, methyl salicylate), or any ingredient in the study formulations. * Pregnancy or breastfeeding. * Use of any antiseptic mouthwash, oral probiotic, or antimicrobial gel in the 3 months prior to baseline.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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College of Dentistry, University of Baghdad
Baghdad, Baghdad Governorate, Iraq