Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New mouthwash could fight gum disease without staining teeth

NCT ID NCT07088666

Disease control Sponsor: University of Pavia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a new mouthwash called MicroRepair ABX works as well as the standard chlorhexidine mouthwash for treating plaque-induced gingivitis (gum inflammation). Forty adults with gum disease used one of the two mouthwashes twice daily for 14 days after a professional cleaning. The goal was to see if MicroRepair ABX could reduce gum pocket depth and plaque with fewer side effects like tooth staining or taste changes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
MicroRepair ABX mouthwash (zinc-hydroxyapatite microcrystals with antibacterial agents)
What this could lead to
If it works, this could offer a gentler alternative to standard mouthwash for managing gum inflammation, with less tooth staining and taste changes.
What could go wrong
This is a small, short-term study with only 40 participants, so results may not apply widely. It also does not test long-term safety or effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Aug 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged between 18 and 70 years * Presence of generalized plaque-induced gingivitis (FMBS ≥ 25%, PPD ≤ 3 mm in ≥90% of sites) * At least 20 natural teeth * Good general health (ASA I or II) * Signed written informed consent * Willingness to comply with study protocol and attend all follow-up visits Exclusion Criteria: * Periodontitis (defined as interdental CAL ≥1 mm at ≥2 non-adjacent teeth) * Systemic diseases affecting periodontal status (e.g., diabetes, immunodeficiencies) * Antibiotic or anti-inflammatory therapy in the last 3 months * Professional dental cleaning in the past 3 months * Pregnancy or breastfeeding * Known allergy to chlorhexidine or microRepair® components * Use of orthodontic appliances or removable prostheses * Smoking more than 10 cigarettes per day * Participation in other clinical trials in the past 6 months

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Dental plaque are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Dental Plaque gingivitis periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental plaque Gingivitis and periodontal diseases Oral hygiene

Contacts and locations

Locations

  • Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

    Pavia, Lombardy, 27100, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.