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Brain zaps may speed recovery after glioma surgery

NCT ID NCT07285525

Symptom relief Sponsor: Beijing Neurosurgical Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive magnetic brain stimulation technique (nrTMS) can help people recover movement in their arm or hand after surgery for a brain tumor called glioma. Forty-three participants who still have weakness 7 days after surgery will receive either real or fake (sham) stimulation daily for a week. The goal is to see if the real treatment leads to faster return of muscle strength and coordination.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 43 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Right-handed. Age between 25 and 65 years old. No history of neurological disease treatment before surgery. Underwent awake surgery with intraoperative direct cortical stimulation or motor evoked potential (MEP) mapping to identify the motor functional area. Postoperative pathology confirmed as newly diagnosed glioma. Eligible for navigated repetitive transcranial magnetic stimulation (nrTMS) rehabilitation treatment. Persistent motor dysfunction (muscle strength or Fugl-Meyer Assessment (FMA) scores not returned to preoperative levels) at 7 days postoperatively. Signed informed consent. Exclusion Criteria: Tumor crossing the midline to the contralateral hemisphere. Excessive head motion (\>1 mm translation or \>1° rotation) during resting-state functional MRI (rs-fMRI) data acquisition. Absence of postoperative motor or language motor deficits. Vulnerable populations (e.g., pregnant women).

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Conditions

The condition(s) this trial relates to.

glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOMA

Contacts and locations

Locations

  • Beijing Tiantan Hospital, Capital Medical University

    Beijing, None Selected, 410008, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.