Brain stimulation for nerve pain: scientists map electrode placement to improve relief
NCT ID NCT06216717
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study looks at how the location of brain-stimulating electrodes affects pain relief in adults with long-term nerve pain that hasn't improved with other treatments. Researchers will use brain scans to see which areas are activated and how that relates to pain reduction. The goal is to better understand why this therapy works and how to make it more effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- motor cortical stimulation
- What this could lead to
- If successful, this could help doctors better target brain stimulation to relieve chronic neuropathic pain that hasn't responded to other treatments.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to new therapies, and results may not apply to all pain patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
adults who were implanted with a motor cortical stimulation system for treatment of chronic neuropathic refractory pain between 2003-2023
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * adults * patient implanted with a motor cortical stimulation system for chronic neuropathic refractory pain, * patient with available postoperative scanner Exclusion Criteria: None
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU NICE
RECRUITINGNice, Alpes Maritimes, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Scientists map the daily rhythms of chronic pain
- Can zapping two brain regions at once quiet chronic nerve pain?
- Can a mindfulness app ease the stress of hospitalization?
- Zapping the brain to loosen stiff legs and quiet nerve pain in MS?
- Ancient Mind-Body practice put to the test for spinal cord injury pain
- Can a skin injection of ketamine and lidocaine tame CRPS pain?