Can Brain-and-Body workouts help Parkinson's patients walk better?
NCT ID NCT07465107
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 12-week exercise program that combines balance, treadmill walking with mental tasks, and leg strengthening can improve gait and balance in people with moderate-to-advanced Parkinson's disease. 48 participants will be randomly assigned to either the exercise program plus usual care, or usual care alone. The main goal is to see if the program is feasible and acceptable, with a future larger study planned if results are promising.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- motor-cognitive exercise program
- What this could lead to
- If it works, this could point toward a practical, drug-free way to improve mobility and reduce falls in people with moderate-to-advanced Parkinson's disease.
- What could go wrong
- This is a small feasibility study (48 people) with no blinding, so results may not be conclusive or generalizable. The exercise program is demanding and may be hard for some participants to complete.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2025
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of PD according to MDS-PD criteria * Aged ≥ 18 years * Informed consent * PD symptoms ≥ 4 years * Independent gait Exclusion Criteria: * Diagnosis of PD Dementia according to the MDS-PD Dementia criteria
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Neurology, Bispebjerg and Frederiksberg Hospital
RECRUITINGCopenhagen NV, 2400, Denmark
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