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Study probes why pain relief fails in sickle cell crisis

NCT ID NCT07246265

Recruiting now Knowledge-focused Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

Summary

This study aims to understand why standard morphine doses often fail to relieve severe pain in adults with sickle cell disease during a crisis. Researchers will measure how quickly patients' kidneys filter morphine to see if faster filtration leads to underdosing. The goal is to create personalized dosing guidelines to provide better pain control for these patients in the intensive care unit.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Le Mans

    NOT_YET_RECRUITING

    Le Mans, 72000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHRU de Tours

    RECRUITING

    Tours, France, 37044, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU d'Orléans

    NOT_YET_RECRUITING

    Orléans, 45067, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Nantes

    NOT_YET_RECRUITING

    Nantes, 44093, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Rennes

    NOT_YET_RECRUITING

    Rennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Henri-Mondor

    NOT_YET_RECRUITING

    Créteil, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

ACUTE CHEST SYNDROME GLOMERULAR HYPERFILTRATION SICKLE CELL DISEASE SICKLE CELL NEPHROPATHY VASO-OCCLUSIVE CRISES