Morning or evening patching for lazy eye? study seeks best timing
NCT ID NCT07294599
First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times
Summary
This study tests whether patching the stronger eye in the morning (8-10 AM) or evening (5-7 PM) works better for improving vision in children with lazy eye (amblyopia). About 100 children aged 4-8 will wear an eye patch for 2-6 hours daily over 6 months. The goal is to see if timing affects how much vision improves, which could make treatment more effective and easier for families.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- eye-patching (occlusion therapy)
- What this could lead to
- If timing matters, this could help doctors prescribe patching at the most effective time of day, improving vision outcomes for children with lazy eye.
- What could go wrong
- This is a small, early-stage trial with only 100 children. The timing difference may have little or no effect on vision, and results may not apply to all types of amblyopia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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84 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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4 to 8 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age: 4-8 years. * Unilateral amblyopia. * Amblyopic-eye BCVA decimal 0.17-0.67 (≈ 6/36-6/9). * Fellow-eye BCVA ≥ 0.80 decimal (≈ 6/7.5 or better). * Amblyopia type: refractive-dominant or strabismic/mixed. * Parent/guardian consent obtained. Exclusion Criteria: * Bilateral amblyopia. * Sensory-deprivation amblyopia (e.g., due to congenital cataract, ptosis, corneal opacity). * Ocular surgery within the past 6 months, or planned surgery during study. * Likely poor adherence (e.g., due to social, logistic, or family constraints).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Irbid Medical Consultation Center
Irbid, Irbid Governorate, 21163, Jordan
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Princess Basma teaching hospital
Irbid, Irbid Governorate, 21163, Jordan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Mixed-Reality headset trains eyes to work together in adults with lazy eye
- A new exercise for the eyes: could it restore 3D vision?
- Video games vs eye patches: a new hope for lazy eye?
- Adult lazy eye may be trainable: brain plasticity under the microscope
- Can a gentle brain zap help adults with lazy eye see better?
- Magnetic pulses to the brain may restore vision in adult lazy eye