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Mindfulness over painkillers? new trial tests meditation for cancer pain

NCT ID NCT05877521

Symptom relief Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a mindfulness program called MORE can help people with long-term cancer pain. 76 adults with a history of cancer and ongoing pain will either learn mindfulness skills or continue their usual care. The goal is to see if this approach is practical and helpful for managing pain without extra medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
mindfulness training (MORE)
What this could lead to
If it works, this could offer a non-drug way to help people with cancer-related chronic pain feel better and cope more easily.
What could go wrong
This is a small, early-phase trial focused on feasibility, not proof of effectiveness. Results may not apply to everyone, and the benefits of mindfulness can vary from person to person.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

76 people

The number who actually took part.

Started

May 2023

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * English speaking * Age ≥ 18 years or older * A history of cancer with no restrictions placed on type of cancer * Determined to be either no-evidence of disease or stable oncological disease by referring or study physicians/advanced practice providers * Having a pain (musculoskeletal, generalized, or neuropathic) rating of 4 or greater in worst pain on a 0-10 numerical rating scale in the preceding week * Having had pain for at least 3 months and at least 15 days with pain in the preceding 30 days * Willing to adhere to all study-related procedures, including randomization to one of two treatment arms: MORE or WLC * Ability to attend video-call session and a quiet/private location Exclusion Criteria: * Active suicidality or schizophrenia * Plan to initiate palliative radiation or interventional pain procedure within the next 12 weeks * Cognitive impairment preventing completing PRO independently or participate in virtual MORE as evaluated by study clinicians

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Conditions

The condition(s) this trial relates to.

Cancer Pain Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer pain Chronic pain

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.