New spray promises lasting hydration for dry skin
NCT ID NCT07271628
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a cosmetic spray called AV0018B to see how well it moisturizes dry skin and how long the effect lasts. Twenty-four women with dehydrated forearms applied the spray six times a day for seven days. Researchers measured skin moisture using a special device and compared the treated area to an untreated area.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AV0018B cosmetic spray
- What this could lead to
- If it works, this could point toward a simple spray to keep dry skin hydrated longer.
- What could go wrong
- This is a very small, early study with only 24 women. It tests a cosmetic product, not a medicine, so any effect is likely modest and temporary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
24 people
The number who actually took part.
- Started
-
Oct 2021
- Finished
-
Oct 2021
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects will be recruited from the panel of the centre (corresponding to an internal computer database whose software has been declared to the Commission Nationale Informatique et Libertés (CNIL)). If necessary, a local announcement/advertising will be done. The subjects corresponding to eligibility criteria may receive a phone call, a letter or an e-mail proposing to participate to the clinical study.
- Ages
-
20 to 55 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Females * Aged 20 to 55 years, inclusive * Phototype I to V, inclusive * Low hairiness and absence of prominent veins on the internal and posterointernal side of the forearms. * No shaving/hair removal of forearms * Dehydrated forearms, with HI ≤ 35 (posterointernal side of the forearms) * Not taking part in another clinical research study. * Having signed the consent form. * Having health insurance. Exclusion Criteria: Population: * Pregnant, breastfeeding women. * Subjects declaring to have hot flushes. * With sunburn on forearms. * Frequently washing their forearms for professional reasons or out of habit. * Application of keratolytic and/or self-tanning products to the upper limbs in the 4 weeks prior to inclusion. * Application of skin care (Hydrating, nourishing) or exfoliating products to the upper limbs in the 2 weeks prior to inclusion. * Application of water or hygiene products to the upper limbs since the last wash on the evening before inclusion. * Participating in another study on the forearms (not including kinetics studies) in the 2 weeks prior to inclusion. * Participating in a kinetics study on the forearms in the 48 hours prior to inclusion. * Subjects unable to comply with the protocol requirements. * Subjects deprived of freedom through a legal or administrative decision, or in care or under legal guardianship. Diseases: * History of allergy to any of the investigational product ingredients * Skin lesions or skin disease on the hands, arms and forearms. * Type 1 diabetes. * Unresolved viral hepatitis. * Chronic cardiovascular, endocrine, rheumatological and urogenital system and non-stabilized neuropsychiatric disorders (treatment started less than 2 months ago). * Acute pathology (infectious, inflammatory). * Dermatological condition or skin lesion on the top of the cheekbone liable to interfere with the samplings according to the investigator's opinion. * Any skin characteristic on the top of the cheekbone incompatible with the samplings (raised nevus, etc.) according to the investigator's opinion. Treatments: * Ongoing local treatment (dermocorticosteroids, retinoids, antibiotics, antifungals, etc.) or treatment applied in the 7 days prior to inclusion. * Ongoing oral antibiotic and/or anti-inflammatory (steroid and non-steroid) or treatment taken for more than 5 consecutive days in the week before inclusion. * Oral treatment (cardiovascular, endocrine, rheumatological, urogenital, neuropsychiatric, immunosuppressant) started in the 2 months prior to inclusion. * Any local treatment applied to the face in the week preceding the inclusion visit * Application of water, any rinsed or leave-on cleansing or care product on the face after the last wash performed the day before the inclusion visit
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Dry skin are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Skin Research Center
Toulouse, France, 31300, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a daily cream rebuild the Skin's barrier? trial puts moisturizer to the test
- Nature's wrinkle fighter? botanical extract put to the test
- Green tea compound EGCG put to the test for clearer, more hydrated skin
- Could probiotic cream soothe Children's dry skin?
- Could a shower gel plus lotion beat lotion alone for dry, itchy skin?
- Bee glue to the rescue? propolis ointment tested for dry skin