Could a 2-Week radiation course replace longer treatment for skin cancer?
NCT ID NCT06998342
First seen Jun 08, 2026 · Last updated Jun 22, 2026 · Updated 2 times
Summary
This study tests whether a short course of radiation (5 treatments over 2 weeks) can prevent cancer from coming back in people with high-risk head and neck skin cancer after surgery. For those with moderate-risk cancer, researchers want to see if simply monitoring them closely is safe instead of giving radiation. The trial will enroll 24 adults and follow them for 2 years to check for recurrence.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Vermont Medical Center
RECRUITINGBurlington, Vermont, 05401, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Short-course radiation therapy (5 treatments over 2 weeks)
What this could lead to
If successful, this could offer a shorter, more convenient radiation option for high-risk skin cancer and show that some patients can safely skip radiation altogether.
What could go wrong
This is a small, early-phase pilot study with only 24 participants, so results may not apply broadly. The active surveillance approach carries a risk of cancer returning without immediate treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.