New test combo could slash unnecessary antibiotics in sepsis
NCT ID NCT05909683
First seen Jan 17, 2026 · Last updated May 18, 2026 · Updated 14 times
Summary
This study tests whether using rapid diagnostic tests (BCID2, Reveal Rapid AST, and PCT) can help doctors choose the right antibiotics faster for patients with severe infections (sepsis). About 190 adults in Greek ICUs will be randomly assigned to either the new test-guided approach or standard care. The goal is to reduce the number of days patients need broad-spectrum antibiotics, which may lower side effects and antibiotic resistance.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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1st Department of Internal Medicine - General Hospital of Athens Sismanoglio- Amalia Fleming
Athens, 15126, Greece
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1st Department of Internal Medicine, General Hospital of Athens KORGIALENIO-BENAKIO E.E.S.
Athens, 11526, Greece
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1st Department of Internal Medicine, General Hospital of Elefsina "Thriasio"
Athens, Elefsina, 19600, Greece
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1st Department of Internal Medicine- General Hospital of Athens GENNIMATAS
Athens, 11527, Greece
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1st University Department of Internal Medicine, AHEPA University General Hospital of Thessaloniki
Thessaloniki, 54636, Greece
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2nd Department of Internal Medicine, General Hospital of Piraeus "Tzaneio"
Piraeus, 18536, Greece
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2nd Department of Internal Medicine, University General Hospital of Alexandroupolis
Alexandroupoli, Greece
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2nd Propaedeutic Department of Internal Medicine, Attikon University Hospital
Athens, Chaidari, 12462, Greece
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3rd Department of Internal Medicine - General State Hospital of Nikaia "Saint Panteleimon" - West Attica General Hospital "Agia Varvara"
Athens, 18454, Greece
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3rd University Department of Internal Medicine, Sotiria Athens General Hospital
Athens, 11527, Greece
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4th Department of Internal Medicine, Attikon University Hospital
Athens, Chaidari, 12462, Greece
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Clinic of Intensive Care and Pulmonary Diseases, Aghioi Anargyroi Kifissia General Oncologic Hospital
Kifissia, 14564, Greece
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Intensive Care Unit of Center for Respiratory Failure, Sotiria Chest Diseases Athens General Hospital
Athens, Attica, 11527, Greece
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Intensive Care Unit, Ippokrateion General Hospital
Thessaloniki, 54642, Greece
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New Multivalent Intensive Care Unit, Sotiria Chest Diseases Athens General Hospital
Athens, Attica, 11527, Greece
Conditions
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