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New combo therapy aims to supercharge immune cells against hard-to-treat melanoma

NCT ID NCT06940739

First seen Dec 12, 2025 · Last updated May 23, 2026 · Updated 22 times

Summary

This study tests a new drug (IOV-3001) that boosts the immune system, given together with a personalized cell therapy (lifileucel) in people with advanced melanoma that has stopped responding to standard treatments. About 42 adults with unresectable or metastatic melanoma will take part. The main goals are to check safety and find the best dose, while also measuring how the drug works in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Greenslopes Private Hospital

    RECRUITING

    Greenslopes, Queensland, 4120, Australia

  • SCRI Oncology Partners- Denver

    RECRUITING

    Denver, Colorado, 80218, United States

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • UNC Hospitals, The University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

Conditions

Explore the condition pages connected to this study.