One drink a day after heart attack? new study puts it to the test

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Hospitalization for acute ST-elevation MI (STEMI) or non ST-elevation MI (NSTEMI) within 365 days prior to screening * Men and women aged ≥18 years who are capable and willing to provide consent * ECG ischemic changes, such as persistent or dynamic ST-segment deviation * Evidence of positive high-sensitive troponin * Confirmation of coronary heart disease aetiology by angiography * Capacity to complete study visits with strict adherence to the protocol assignment * Self-reported average alcohol consumption of between 1 and 28 standard units per week in the 12 months prior to the index hospitalization. Exclusion Criteria: * High alcohol consumption, defined as an average of \>28 alcoholic standard units/week in the 12 months prior to the index hospitalization * Alcohol use disorder (AUDIT score \>20 at screening) * History of alcohol or substance abuse * Naïve to alcohol consumption * Light alcohol consumption (\<1 standard units by week) * Prior severe heart failure (NYHA III-IV) * Severe LV dysfunction at screening (\<30%) * History of gastric ulcer or gastro-intestinal bleeding * Serious chronic liver disease or liver test elevation (\> 3 times upper limit normal range) * Personal history of any colon or liver cancer * Any active malignancy (less than 5 years or ongoing treatment) * Estimated glomerular filtration rate 15 ml/min/1.73m² or end-stage renal disease * Any medication (investigator's discretion) making study participation impractical or precluding required follow-up * History of organ transplant * Participation in another trial testing intervention on similar CV outcomes (investigator's discretion) * Any medical, geographic, or social factor making study participation impractical or precluding required follow-up. * Pregnant, breastfeeding or planning to become pregnant within 12 months.