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Zoom therapy aims to ease depression and prevent HIV in transgender romanians

NCT ID NCT06229132

Symptom relief Sponsor: Columbia University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested a 16-session online therapy program for transgender and gender-diverse adults in Romania who had symptoms of depression or anxiety. The therapy was designed to address stress related to discrimination and lack of affirming healthcare, and also included HIV prevention support. The goal was to see if the program was feasible and could improve mental health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
LGBTQ-affirmative cognitive behavioral therapy (CBT) delivered via Zoom
What this could lead to
If it works, this could point toward a scalable mental health and HIV prevention tool for transgender communities in low-resource settings.
What could go wrong
This was a very small, one-arm trial with only 25 participants, so results may not apply broadly. The intervention is behavioral and may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

25 people

The number who actually took part.

Started

Mar 2022

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. report an identity as transgender or gender expansive (e.g., gender non-binary) and a gender that is different from their assigned sex at birth; 2. be ≥18 years old; 3. report a score of ≥2.5 on either the two items measuring depression symptoms or the two items measuring anxiety symptoms using the Brief Symptom Inventory (BSI-4); and 4. reside in Romania for the duration of the study (approximately 6 months). Exclusion Criteria: 1. active suicidality, mania, or psychosis and 2. having received CBT in the prior 12 months.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder HIV infectious disease Psychological Well-Being Suicidal Ideation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Depression HIV Suicidality Transgender

Contacts and locations

Locations

  • Columbia University School of Nursing

    New York, New York, 10032, United States

More trials for these conditions

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