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Blood test ratio may spot deadly lung clots faster

NCT ID NCT07023705

Diagnosis Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a ratio of two blood cell types (monocytes and large platelets) can help diagnose acute pulmonary embolism, a serious blood clot in the lungs. Researchers analyzed blood samples from 53 patients who had a CT scan to confirm or rule out the clot. The goal was to see if this simple, inexpensive test could be a useful diagnostic tool.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could provide a quick, inexpensive blood test to help doctors diagnose pulmonary embolism faster.
What could go wrong
This is a small, retrospective study with only 53 participants. The results need to be confirmed in larger, more diverse groups before it can be used in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

53 people

The number who actually took part.

Started

Jan 2024

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients presenting to the emergency department with signs and symptoms of pulmonary embolism who underwent CT pulmonary angiography for diagnosis.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Only patients with the results of full blood count and white blood cell differentiation, measured before the treatment of suspected PE. * Patients underwent CT pulmonary angiography to confirm or exclude pulmonary embolism diagnosis. Exclusion Criteria: * Patient with history of any myeloproliferative disorder, myelofibrosis, Glanzmann thrombasthenia, May-Hegglin anomaly, Bernard-Soulier syndrome, suspicion of disseminated intravascular coagulation. * Patient receiving any anticoagulant drug at a therapeutic dose. * Patient with blood transfusion in the last 2 months. * Patients with acute coronary syndrome, pulmonary edema. * Patient on immunosuppressive drugs , Oral contraceptive pills . * Patients with severe renal or hepatic disease. * Patients with Stroke. * Patients with malignancy.

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Conditions

The condition(s) this trial relates to.

disease pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diagnosis Pulmonary embolism (diagnosis)

Contacts and locations

Locations

  • Ain Shams University

    Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.