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New pill could tame severe gut disease

NCT ID NCT07463183

First seen Mar 21, 2026 · Last updated May 20, 2026 · Updated 11 times

Summary

This study tests an experimental drug called MK-8690 for people with moderate to severe ulcerative colitis, a chronic gut condition causing inflammation and symptoms like diarrhea and bleeding. About 100 adults will receive either the drug or a placebo to see if it can bring about remission—meaning less inflammation and fewer symptoms—after 12 weeks. The goal is to find a new treatment option for those who haven't responded well to existing therapies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BVL Research - Kansas ( Site 1054)

    RECRUITING

    Liberty, Missouri, 64068, United States

    Contact Phone: •••-•••-••••

  • Clinnova Research ( Site 1042)

    RECRUITING

    Anaheim, California, 92805, United States

    Contact Phone: •••-•••-••••

  • Gastroenterology Associates of Central Georgia ( Site 1060)

    RECRUITING

    Macon, Georgia, 31201, United States

    Contact Phone: •••-•••-••••

  • Nature Coast Clinical Research ( Site 1045)

    RECRUITING

    Inverness, Florida, 34452, United States

    Contact Phone: •••-•••-••••

  • Peak Gastroenterology Associates ( Site 1052)

    RECRUITING

    Colorado Springs, Colorado, 80907, United States

    Contact Phone: •••-•••-••••

  • Research Associates of South Florida - Miami - Southwest 8th Street ( Site 1072)

    RECRUITING

    Miami, Florida, 33134, United States

    Contact Phone: •••-•••-••••

  • South Denver Gastroenterology, PC ( Site 1068)

    RECRUITING

    Englewood, Colorado, 80113, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.