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New drug MK-8189 tested for Alzheimer's agitation and psychosis

NCT ID NCT05227118

First seen May 01, 2026 · Last updated May 17, 2026 · Updated 2 times

Summary

This early-stage study tested the safety of a drug called MK-8189 in 29 people with Alzheimer's disease, some of whom also had symptoms of agitation or psychosis. The main goal was to see if the drug was safe and tolerable. This is a first step toward finding new treatments for these challenging symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Atlanta Center for Medical Research ( Site 0004)

    Atlanta, Georgia, 30331, United States

  • CITrials ( Site 0007)

    Santa Ana, California, 92705, United States

  • Global Medical Institutes LLC; Princeton Medical Institute ( Site 0008)

    Princeton, New Jersey, 08540, United States

  • Richmond Behavioral Associates ( Site 0003)

    Staten Island, New York, 10314, United States

  • Top Medical Research ( Site 0005)

    Cutler Bay, Florida, 33189, United States

  • Velocity Clinical Research, Hallandale Beach ( Site 0001)

    Hallandale, Florida, 33009, United States

  • Well Pharma Medical Research, Corp. ( Site 0006)

    Miami, Florida, 33173, United States

  • iResearch Atlanta ( Site 0009)

    Decatur, Georgia, 30030, United States

Conditions

Explore the condition pages connected to this study.