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Virtual reality workouts may keep aging brains fit

NCT ID NCT07652996

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether an 8-week mixed reality exercise program could improve thinking and physical abilities in adults aged 60 and older with mild cognitive decline. Thirty participants were split into two groups: one did mixed reality cognitive-physical training, the other did standard exercises like aerobics and Tai Chi. Researchers measured changes in memory, attention, balance, and strength.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mixed reality motor-cognitive exercise (MR-MCT) and multimodal exercise (functional fitness + Tai Chi)
What this could lead to
If it works, this could point toward a fun, engaging way to help older adults stay sharp and active.
What could go wrong
This is a small, early study with only 30 participants, so results may not apply to everyone. The effect on thinking and physical function may be small or not last long.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Feb 2026

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. age 60 years or older; 2. self-determined to be able to exercise safely; 3. voluntarily completing all study activities; 4. voluntarily signing the informed consent; 5. willing to be randomized to either MR-MCT intervention group or the active comparison group; and 6. meeting one of the following criteria: 1. having subjective cognitive decline (self-report) or MCI: indicated by a Mini-Cog TM score of \<4 to increase sensitivity of MCI; 2. exhibiting pre-physical frailty or physical frailty, as indicated by a score of 1-2 (pre-frailty) or 3-5 (frailty) on the 5-item FRAIL scale. 3. low physical activity, defined as less than 600 Metabolic Equivalent of Task (MET)-min/week and fewer than two 10-min sessions of strengthening exercises per week in the past three months on the International Physical Activity Questionnaire -Short Form (IPAQ-SF) with Muscle Strength. Exclusion Criteria: 1. recent history of myocardial infarction, stroke, or physical limitations as identified on the Physical Activity Readiness Questionnaire (PARQ); 2. Severe obesity: Body mass index (BMI) of 40 or higher; or 3. concurrent participation in another intervention study.

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • School of Kinesiology, University of Michigan

    Ann Arbor, Michigan, 48109-1048, United States