Could a Mitochondria-Targeting pill ease asthma in obesity?
NCT ID NCT04026711
First seen Jan 10, 2026 · Last updated Jun 22, 2026 · Updated 23 times
Summary
This early-phase trial tested whether MitoQ, a drug that targets cell powerhouses, can improve airway function in 47 obese adults with poorly controlled asthma. Participants took MitoQ or a placebo daily for 12 weeks. The main goal was to see if MitoQ reduces airway reactivity, a key asthma problem.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Duke University
Durham, North Carolina, 27710, United States
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University of Vermont
Burlington, Vermont, 05405, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MitoQ (mitoquinol)
What this could lead to
If it works, this could point toward a new treatment option for obese people with hard-to-control asthma.
What could go wrong
This is a small, early-phase pilot study with only 47 participants. The results may not apply to all asthma patients, and MitoQ might not improve symptoms significantly.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.