Can watching brain waves reveal early signs of developmental delays?
NCT ID NCT03307317
First seen Jun 24, 2026 · Last updated Sep 09, 2026 · Updated 11 times
Summary
This observational study looks at how the brain responds when watching others perform actions, focusing on the mirror neuron system. Researchers will measure brain activity in healthy adults and infants, including those at risk for developmental delays, using EEG and fNIRS. The goal is to understand typical development and identify early markers of neurodevelopmental disorders.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2018
- Expected to finish
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Feb 2031
An estimate. End dates often move.
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult pilots and TD infants will be recruited from a community sample. AR infants will be recruited from local early intervention providers and pediatricians, following procedures of ongoing collaborative studies at NIH.
- Ages
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9 months to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* INCLUSION CRITIERIA: Healthy adults * Age of 18-65 at study entry * Healthy and good condition as determined by medical history and physical examination Healthy Infants * 9 months +/- 2 weeks of age at time of consent * Healthy and good condition as determined by medical history and physical examination * Age appropriate development as determined by parent report and exam * Full term at birth * Normal weight for gestational age At Risk Infants * 12 months +/- 2 weeks at the time of consent * Must have at least one of the following: observed developmental delay; sibling of a child with autism; premature birth; small for gestational age EXCLUSION CRITERIA: Healthy Adults * Uncorrected auditory impairment * Uncorrected visual impairment * Head injury with loss of consciousness * Inability to provide consent * Subject has a condition, that in the opinion of the investigator, creates an unacceptable risk for participation Healthy and At-Risk Infants * A language other than English as the primary language spoken at home * Having a medical impairment that interferes with study participation such as having a g-tube, shunt or seizure disorder and inability to hold one s head upright * Having a known visual impairment * Having a known auditory impairment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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