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Heart surgery brain fog: scientists hunt for a blood test to predict it

NCT ID NCT07231731

First seen Nov 17, 2025 · Last updated Jun 10, 2026 · Updated 32 times

Summary

This study looked at 48 older adults having heart bypass surgery to see if a small molecule called microRNA-151-5p is linked to memory and thinking problems after the operation. Researchers measured levels of this molecule and inflammation in the blood before and after surgery, and tested thinking skills daily. The goal was to understand why some people experience cognitive decline after heart surgery and find early warning signs.

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Contacts and locations

Locations

  • University Hospital Osijek

    Osijek, 31000, Croatia

Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction coronary artery disorder Inflammation nervous system disorder Neuroinflammatory Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Cognitive Complications Postoperative Complications psychiatric disorder Systemic Inflammatory Response Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.