Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Scientists hunt for clues to kidney damage in sepsis

NCT ID NCT06498336

Knowledge-focused Sponsor: University Hospital Ostrava Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 211 people with sepsis, some of whom also had acute kidney injury. Researchers measured specific microRNAs and other markers in the blood to understand how kidney damage happens. The goal was to find new targets for diagnosis or treatment, not to test a therapy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new ways to diagnose or treat septic acute kidney injury.
What could go wrong
This is an observational study, not a treatment trial. It only measures molecules in the blood, so it cannot prove any therapy works.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

211 people

The number who actually took part.

Started

May 2024

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Critically ill adult patients suffering from sepsis defined according to SEPSIS 3 definition, with or without acute kidney injury defined by KDIGO 2012 (2) and healthy volunteers

Ages

18 to 100 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: The study group of patients with sepsis with or without acute kidney injury * age \> 18 years * newly diagnosed sepsis or septic shock with or without acute kidney injury Healthy volunteers * no evidence of infection on clinical or laboratory examination * age \> 18 years * signed informed consent Exclusion Criteria: The study group of patients with sepsis with or without acute kidney injury * age \< 18 years * chronic kidney disease at stage 4 or 5 according to KDIGO recommendations (KDIGO) for chronic kidney disease 2024 * patients on chronic dialysis treatment, or after renal transplantation Healthy volunteers * acute or chronic infection * renal disease

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Acute kidney injury are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

acute kidney injury infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury Acute kidney injury due to sepsis Sepsis

Contacts and locations

Locations

  • University Hospital Olomouc

    Olomouc, Olomouc Region, 779 00, Czechia

  • University Hospital Ostrava

    Ostrava, Moravian-Silesian Region, 708 52, Czechia

More trials for these conditions

Other studies related to the condition(s) this trial covers.