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Can a sugar pill and meditation ease chronic pain? new study investigates

NCT ID NCT06720909

Symptom relief Sponsor: Arizona State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study looks at whether combining mindfulness training (MBSR) with an open-label placebo—a pill that patients know has no active drug—is a practical way to help people with chronic pain. Researchers will randomly assign 45 adults to receive either mindfulness alone, the placebo alone, or both together. The main goal is to see if people stick with the treatments and find them acceptable, not yet to measure pain relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
open-label placebo (sugar pill with no hidden deception)
What this could lead to
If it works, this could point toward a simple, low-cost way to improve chronic pain management by combining mind-body techniques with honest placebo use.
What could go wrong
This is a very early feasibility study with only 45 participants. It is not designed to prove the treatment works, only that it can be done. Results may not apply to everyone with chronic pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. ≥18 years old; 2. ability to speak, write, and read in English; 3. physical pain present on at least half the days in the past 3 months; and 4. average past week pain severity rating ≥3 on a 0-10 Numerical Rating Scale. Exclusion Criteria: 1. acute pain due to recent injury or surgery; 2. self-reporting of chronic malignant pain (e.g., cancer, HIV); 3. self-reporting of Raynaud's disease (those who can be contraindicated for cold pressor testing); 4. severe psychopathology (e.g., a psychotic disorder) or significant cognitive deficits judged to interfere with study procedures; 5. currently pregnant or breastfeeding; 6. inability to discontinue use of vitamin B2 supplements or a multivitamin containing vitamin B2 throughout the study period (these interfere with riboflavin tracer-OLP treatment adherence-monitoring); 7. inability to commit to study period.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain

Contacts and locations

Locations

  • Arizona State University

    Phoenix, Arizona, 85004, United States

  • Arizona State University Downtown Phoenix Campus

    Phoenix, Arizona, 85004, United States

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