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Mindfulness may alter brain metabolism, small study hints

NCT ID NCT05710250

Knowledge-focused Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a 6-week mindfulness meditation program can change brain metabolism in areas linked to memory. Thirty female students were randomly assigned to either mindfulness training or muscle relaxation. Researchers used brain scans to measure chemicals like glutamate and tested memory performance before and after the program.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mindfulness-Based Stress Reduction (MBSR) program
What this could lead to
If successful, this could help explain how mindfulness meditation improves memory and academic performance by changing brain chemistry.
What could go wrong
This is a small, early study with only 30 female students, so results may not apply to everyone. It measures brain changes, not long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jan 2023

Finished

Apr 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Female * Right-handed * ≥ 18 years old * Affiliated to a social security scheme * Written consent signed by the participan Exclusion Criteria: * Inability to complete the entire study programme * Previous participation in an MBSR or MBCT programme * Current neurological pathology * Current psychiatric pathology, score ≥ 3 on the PHQ-4 self-questionnaire * Previous or ongoing psychological or psychiatric treatment * Previous or current psychotropic treatment * Usual contraindications to brain MRI (including claustrophobia, ocular metallic foreign body, pacemaker, neurostimulator, cochlear implants (or non-removable electronic medical equipment), old generation heart valves, vascular clips previously implanted on a cranial aneurysm). * Pregnancy * During the exclusion period of a clinical research study * Under legal protection or deprived of liberty.

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Conditions

The condition(s) this trial relates to.

Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Behavior

Contacts and locations

Locations

  • Clinical Investigation Center

    Tours, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.