Can mindfulness help young adults with a high cancer risk?
NCT ID NCT07032922
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a mindful self-compassion program could be adapted for young adults aged 18 to 29 with Li-Fraumeni syndrome, a genetic condition that greatly raises cancer risk. Seven participants attended a one-day demonstration and gave feedback on how to make the program more helpful. The goal was to learn how to better support their mental health, not to treat or cure the condition.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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7 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Oct 2025
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study will enroll up to 14 Young Adults with Li-Fraumeni Syndrome and up to 6 key stakeholders.
- Ages
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18 to 29 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* INCLUSION CRITERIA: To be eligible to participate in this study, YAs must meet all of the following criteria: * Self-reported diagnosis of LFS. * Aged 18 to 29 years at the time of enrollment. * Ability to speak, read, and/or write in English (to understand and provide informed consent and participate in the study activities). * Currently live in the U.S. * Willing to engage in a demonstration of a mental health resource for YAs with LFS and provide feedback on it. * Able to travel to the NCI Shady Grove Campus. * Access to a computer, high-speed internet, and a webcam, which may be necessary if the study team cannot conduct the study at the NCI due to unforeseen circumstances (e.g., government policy, weather). * Have not participated in a mindfulness- or compassion-based program within the past 6 months. * Do not have a consistent meditation practice \>= 30 minutes per day. Eligibility based on these inclusion criteria will be determined via an online screening questionnaire. To be eligible to participate in this study, non- YA stakeholders must meet all of the following criteria: * At least age 18 at the time of enrollment. * Ability to speak, read, and/or write in English (to understand and provide informed consent and participate in the study activities). * Currently live in the U.S. * Willing to observe a demonstration of a mental health resource for YAs with LFS and provide feedback on it. * Able to travel to the NCI Shady Grove Campus. * Access to a computer, high-speed internet, and a webcam, which may be necessary if the study team cannot conduct the study at the NCI due to unforeseen circumstances (e.g., government policy, weather). EXCLUSION CRITERIA: A YA who meets the following criteria will be excluded from participation in this study: * A Patient Health Questionnaire (PHQ-9) score or a General Anxiety Disorder (GAD-7) score \>= 15 at the time of screening. Scores \>= 15 correspond to moderately severe or severe depression and severe anxiety, respectively. The PHQ-9 and GAD-7 are standardized, validated measures of depression and anxiety. The data obtained from participants who are determined to be ineligible will not be retained in the database or system. Instead, it will be destroyed to ensure the privacy and confidentiality of the participants. * Individuals who do not meet eligibility criteria listed. A non-YA stakeholder who meets any of the following criteria will be excluded from participation in this study: -Individuals who do not meet eligibility criteria listed. No other exclusionary criteria apply.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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NCI Shady Grove Campus
Rockville, Maryland, 20850, United States
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Other studies related to the condition(s) this trial covers.
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