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Can mindfulness help young adults with a high cancer risk?

NCT ID NCT07032922

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a mindful self-compassion program could be adapted for young adults aged 18 to 29 with Li-Fraumeni syndrome, a genetic condition that greatly raises cancer risk. Seven participants attended a one-day demonstration and gave feedback on how to make the program more helpful. The goal was to learn how to better support their mental health, not to treat or cure the condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

7 people

The number who actually took part.

Started

Jun 2025

Finished

Oct 2025

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study will enroll up to 14 Young Adults with Li-Fraumeni Syndrome and up to 6 key stakeholders.

Ages

18 to 29 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: To be eligible to participate in this study, YAs must meet all of the following criteria: * Self-reported diagnosis of LFS. * Aged 18 to 29 years at the time of enrollment. * Ability to speak, read, and/or write in English (to understand and provide informed consent and participate in the study activities). * Currently live in the U.S. * Willing to engage in a demonstration of a mental health resource for YAs with LFS and provide feedback on it. * Able to travel to the NCI Shady Grove Campus. * Access to a computer, high-speed internet, and a webcam, which may be necessary if the study team cannot conduct the study at the NCI due to unforeseen circumstances (e.g., government policy, weather). * Have not participated in a mindfulness- or compassion-based program within the past 6 months. * Do not have a consistent meditation practice \>= 30 minutes per day. Eligibility based on these inclusion criteria will be determined via an online screening questionnaire. To be eligible to participate in this study, non- YA stakeholders must meet all of the following criteria: * At least age 18 at the time of enrollment. * Ability to speak, read, and/or write in English (to understand and provide informed consent and participate in the study activities). * Currently live in the U.S. * Willing to observe a demonstration of a mental health resource for YAs with LFS and provide feedback on it. * Able to travel to the NCI Shady Grove Campus. * Access to a computer, high-speed internet, and a webcam, which may be necessary if the study team cannot conduct the study at the NCI due to unforeseen circumstances (e.g., government policy, weather). EXCLUSION CRITERIA: A YA who meets the following criteria will be excluded from participation in this study: * A Patient Health Questionnaire (PHQ-9) score or a General Anxiety Disorder (GAD-7) score \>= 15 at the time of screening. Scores \>= 15 correspond to moderately severe or severe depression and severe anxiety, respectively. The PHQ-9 and GAD-7 are standardized, validated measures of depression and anxiety. The data obtained from participants who are determined to be ineligible will not be retained in the database or system. Instead, it will be destroyed to ensure the privacy and confidentiality of the participants. * Individuals who do not meet eligibility criteria listed. A non-YA stakeholder who meets any of the following criteria will be excluded from participation in this study: -Individuals who do not meet eligibility criteria listed. No other exclusionary criteria apply.

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Conditions

The condition(s) this trial relates to.

Li-Fraumeni syndrome Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NCI Shady Grove Campus

    Rockville, Maryland, 20850, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.