Parkinson's diet study: could the MIND diet ease symptoms?
NCT ID NCT06207136
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether following a Mediterranean-style diet for 18 months is practical and beneficial for people with Parkinson's disease. Researchers will see if the diet is easy to stick with and if it leads to changes in gut bacteria or Parkinson's symptoms. About 40 participants without dementia will be randomly assigned to either the special diet or a standard diet, with coaching and cooking classes provided online.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Eligible if the person living with Parkinson's has/is: 1. a clinical diagnosis of PD, 2. cognitively stable (no clinical dementia), 3. between 40-80 years old, 4. able to travel to UBC for 6 onsite visits over 18 months, 5. sufficient English proficiency (coaching and cooking classes are in English only), 6. on a stable dopaminergic medication for at least one month before baseline, 7. computer and internet access at home, and can be available via video link for at least 80% of the study sessions. Exclusion Criteria: Not eligible, if person has/is: 1. a diagnosis of atypical parkinsonism, 2. medical or psychiatric conditions that would prevent full participation in the nutrition intervention (such as food allergies), significant dysphagia, diabetes on insulin, anti-coagulation on warfarin, and inflammatory bowel disease, 3. clinical dementia, 4. unable to complete questionnaires or understand study instructions, 5. using of immunomodulatory agents, 6. used Probiotics in the last 4 weeks prior to study start, 7. used Antibiotics in the last 3 months prior to study start, 8. contraindications for MRI.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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UBC Pacific Parkinson's Research Centre
RECRUITINGVancouver, British Columbia, V6T 2B5, Canada
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