Could a heart drug save brain function after a bleed?

NCT ID NCT04362527

Completed Disease control Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 01, 2026 · Updated 26 times

Summary

This study tested whether a drug called milrinone, given through an IV, can help people recover better from a dangerous complication of a brain bleed. The complication, called vasospasm, causes blood vessels in the brain to tighten and can lead to stroke or death. The trial involved 370 adults who had a brain bleed and developed vasospasm. Half received milrinone and half received a placebo, and researchers measured how many had a good recovery after 3 months.

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Contacts and locations

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Locations

APHP Lariboisière

Paris, France
CHU Angers

Angers, France
CHU Besançon

Besançon, France
CHU Bordeaux

Bordeaux, France
CHU Brest

Brest, France
CHU Caen

Caen, France
CHU Dijon

Dijon, France
CHU Lille

Lille, France
CHU Nantes

Nantes, France
CHU Rennes

Rennes, France
CHU Tours

Tours, France
Hôpital Civils de Lyon

Lyon, France
Hôpital Fondation ROTHSCHILD

Paris, France
Hôpital Gabriel Montpied

Clermont-Ferrand, France
Hôpital Gui de Chauliac

Montpellier, France
Hôpital de Hautepierre

Strasbourg, 67098, France

Conditions

Explore the condition pages connected to this study.

VASOSPASM