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Personalized exercises may ease migraine pain and fatigue

NCT ID NCT07261384

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a personalized physiotherapy program—including manual therapy, neck exercises, balance training, and pain education—can reduce pain, fatigue, and improve physical function in people with migraine. Fifty adults aged 18-55 with 2-8 migraine attacks per month will be randomly assigned to either the tailored program or standard physiotherapy for 8 weeks. Outcomes will be measured at the start, after treatment, and at follow-up.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
personalized physiotherapy program including manual therapy, cervical stabilization exercises, vestibular rehabilitation, and pain neuroscience education
What this could lead to
If it works, this could offer a non-drug way to ease migraine pain, fatigue, and improve daily function.
What could go wrong
This is a small, early-stage trial with only 50 people. Results may not apply to everyone, and the benefit over standard care is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged between 18 and 55 years * Diagnosed with migraine according to the International Classification of Headache Disorders - 3rd edition (ICHD-3) criteria * Experiencing 2-8 migraine attacks per month in the last 3 months * Able to participate in an 8-week physiotherapy intervention program * Able to understand instructions and provide written informed consent * Stable medication use for migraine for at least 1 month prior to participation (no changes planned during study period) Exclusion Criteria: * • Presence of other primary headache disorders (cluster headache, tension-type headache as primary diagnosis, etc.) * Neurological diseases (epilepsy, stroke, multiple sclerosis) * Vestibular disorders unrelated to migraine * Cervical radiculopathy, myelopathy, or severe cervical spine pathology * History of neck surgery or significant cervical trauma * Severe musculoskeletal conditions affecting posture or cervical function * Pregnancy or breastfeeding * Participation in another clinical trial within the last 3 months * Inability to attend intervention sessions or complete outcome assessments

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Conditions

The condition(s) this trial relates to.

Fatigue migraine disorder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Erzincan Binali Yıldırım Univercity, Medicine Faculty

    Erzincan, 24000, Turkey (Türkiye)

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