Personalized exercises may ease migraine pain and fatigue
NCT ID NCT07261384
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a personalized physiotherapy program—including manual therapy, neck exercises, balance training, and pain education—can reduce pain, fatigue, and improve physical function in people with migraine. Fifty adults aged 18-55 with 2-8 migraine attacks per month will be randomly assigned to either the tailored program or standard physiotherapy for 8 weeks. Outcomes will be measured at the start, after treatment, and at follow-up.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- personalized physiotherapy program including manual therapy, cervical stabilization exercises, vestibular rehabilitation, and pain neuroscience education
- What this could lead to
- If it works, this could offer a non-drug way to ease migraine pain, fatigue, and improve daily function.
- What could go wrong
- This is a small, early-stage trial with only 50 people. Results may not apply to everyone, and the benefit over standard care is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged between 18 and 55 years * Diagnosed with migraine according to the International Classification of Headache Disorders - 3rd edition (ICHD-3) criteria * Experiencing 2-8 migraine attacks per month in the last 3 months * Able to participate in an 8-week physiotherapy intervention program * Able to understand instructions and provide written informed consent * Stable medication use for migraine for at least 1 month prior to participation (no changes planned during study period) Exclusion Criteria: * • Presence of other primary headache disorders (cluster headache, tension-type headache as primary diagnosis, etc.) * Neurological diseases (epilepsy, stroke, multiple sclerosis) * Vestibular disorders unrelated to migraine * Cervical radiculopathy, myelopathy, or severe cervical spine pathology * History of neck surgery or significant cervical trauma * Severe musculoskeletal conditions affecting posture or cervical function * Pregnancy or breastfeeding * Participation in another clinical trial within the last 3 months * Inability to attend intervention sessions or complete outcome assessments
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Erzincan Binali Yıldırım Univercity, Medicine Faculty
Erzincan, 24000, Turkey (Türkiye)
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