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Scientists to test if PACAP-38 sparks migraine aura in new study

NCT ID NCT07342296

First seen Jan 16, 2026 · Last updated May 20, 2026 · Updated 17 times

Summary

This study looks at whether a natural brain chemical called PACAP-38 can bring on migraine aura (like visual disturbances) in people who already get migraines with aura. 21 adults with a history of migraine with aura will receive either PACAP-38 or a placebo. Researchers will watch for 12 hours to see if aura or headache occurs. The goal is to better understand what causes migraine aura, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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