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Can targeted supplements ease migraine suffering? new trial investigates

NCT ID NCT07634146

Disease control Sponsor: Miracle Wellness LLC Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a set of dietary supplements taken at different phases of a migraine cycle can improve quality of life and reduce headache days in adults with migraine. Participants take a daily foundational supplement, with additional supplements during the luteal phase (for women with menstrual migraine) and during migraine attacks. The trial compares the supplement regimen to a sham supplement and usual care alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dietary supplement regimen (foundational, luteal phase, and migraine phase supplements)
What this could lead to
If effective, this supplement regimen could offer a natural option to reduce migraine impact and improve daily functioning.
What could go wrong
This is an early-stage trial with no drug approval; supplements are not regulated like medications, and results may not apply to all migraine types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 920 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Self-reported history of migraine, based on the International Headache Society (IHS) International Classification of Headache Disorders, 3rd edition (ICHD-3) diagnostic criteria for migraine. * Being able to take oral supplements. * Agreeing to maintain their regular lifestyle. * Access to internet and telephone. Exclusion Criteria: * Pregnancy or lactation. * Presence of any active medical condition or diagnosis other than episodic migraine, including liver or kidney disease or condition. * Use of overlapping supplements or interacting medications. * Known allergies to study ingredients. * Daily use of alcohol, tobacco, or recreational drugs. * Participation in any other clinical or interventional study within 30 days prior to baseline or concurrently.

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Conditions

The condition(s) this trial relates to.

Headache migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Menstrual migraine Menstrual migraine (MM) headaches Migraine Migraine disability Migraine disease Migraine disorder Migraine headache Migraine in adults

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Natural Migraceuticals

    Lutherville-Timonium, Maryland, 21093, United States

    Contact Email: •••••@•••••

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