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TTP Patients' hidden vessel damage revealed by advanced scans

NCT ID NCT07615244

First seen May 30, 2026

Summary

This study aims to measure damage to tiny blood vessels in people with thrombotic thrombocytopenic purpura (TTP), both during active disease and in remission. Researchers will use brain MRI, eye scans, and nailfold capillary exams to detect abnormalities. 79 participants will be followed for three years with five study visits. No drugs are being tested; the goal is to better understand how TTP affects the body's microcirculation over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

    Milan, Milano, 20122, Italy

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better understand and monitor organ damage in TTP patients, potentially improving long-term care.

What could go wrong

This is an observational study with no treatment being tested, so it will not directly lead to a new therapy. The results may not apply to all TTP patients.

Conditions

The condition(s) this trial relates to.

thrombotic thrombocytopenic purpura

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.