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Tiny plastics in our food may fuel Crohn's inflammation, scientists investigate

NCT ID NCT07630883

Knowledge-focused Sponsor: Mak Wing Yan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will look at whether tiny plastic particles found in food and water are linked to Crohn's disease. Researchers will compare 90 people—some with Crohn's and some without—to see if those with Crohn's have more plastic particles in their blood and gut, and how that affects their immune system and gut bacteria. The goal is to understand if these plastics contribute to inflammation, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal whether microplastics play a role in Crohn's disease, pointing toward new ways to manage or prevent flare-ups.
What could go wrong
This is a small, early-stage pilot study that only observes and measures—it does not test a treatment. Results may not lead to direct health changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Dec 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Potential subjects will be identified at the Department of Medicine and Therapeutics of the Prince of Wales Hospital, or by personal referral from staff.

Ages

18 to 80 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Cases: * Age 18-80 years * Confirmed diagnosis of Crohn's disease (for cases) * Ability to provide informed consent. Control: * Age 18-80 years old * No history of major large bowel resection * Ability to provide informed consent. Exclusion Criteria: Cases: * Antibiotic/probiotic use within 4 weeks * History of gastrointestinal malignancy * Presence of stoma * Currently Pregnant * Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure Control: * Currently Pregnant * Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure * Inability in giving consent

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Crohn's disease (CD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Prince of Wales Hospital

    Hong Kong, Hong Kong

More trials for these conditions

Other studies related to the condition(s) this trial covers.