Vitamin D3 and microneedling: a new hope for alopecia areata?
NCT ID NCT07243977
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two treatments for alopecia areata, a condition causing patchy hair loss. One group receives microneedling alone, while the other gets microneedling plus topical vitamin D3. The goal is to see if adding vitamin D3 leads to complete hair regrowth. Eighty adults aged 18-60 with localized alopecia areata will be treated every two weeks for six sessions and followed for three months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin D3 (cholecalciferol) topical solution
- What this could lead to
- If it works, this could offer a safe, affordable, and non-invasive treatment option for patchy hair loss due to alopecia areata.
- What could go wrong
- This is a small, early-stage study with only 80 participants. Results may not apply to everyone, and the combination may not be more effective than microneedling alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
80 people
The number who actually took part.
- Started
-
Mar 2025
- Expected to finish
-
Dec 2025
An estimate. End dates often move.
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients diagnosed with Alopecia Areata and have not received any treatment for last 4 weeks. * Age range of 18-60 years * Both male and female patients Exclusion Criteria: * Active infection or atrophy of scalp due to previous treatment * Patients with alopecia universalis or totalis. * Pregnant or lactating mothers. * Systemic co-morbidities like diabetes, hypertension, chronic liver or kidney disease and immunosuppression * Unwilling or uncooperative patients
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Services Institute of Medical Sciences, Lahore
Lahore, Punjab Province, 54000, Pakistan
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Other studies related to the condition(s) this trial covers.
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