Vitamin D3 and microneedling: a new hope for alopecia areata?

NCT ID NCT07243977

Ongoing Disease control Sponsor: Services Institute of Medical Sciences, Pakistan Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for alopecia areata, a condition causing patchy hair loss. One group receives microneedling alone, while the other gets microneedling plus topical vitamin D3. The goal is to see if adding vitamin D3 leads to complete hair regrowth. Eighty adults aged 18-60 with localized alopecia areata will be treated every two weeks for six sessions and followed for three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D3 (cholecalciferol) topical solution
What this could lead to: If it works, this could offer a safe, affordable, and non-invasive treatment option for patchy hair loss due to alopecia areata.
What could go wrong: This is a small, early-stage study with only 80 participants. Results may not apply to everyone, and the combination may not be more effective than microneedling alone.

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Conditions

The condition(s) this trial relates to.

alopecia areata

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALOPECIA AREATA

Contacts and locations

Locations

Services Institute of Medical Sciences, Lahore

Lahore, Punjab Province, 54000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.