Gut bugs may boost bowel healing after short gut surgery
NCT ID NCT07530055
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether certain gut bacteria help the remaining intestine absorb nutrients better after surgery for short bowel syndrome. Researchers will follow 15 adults who are having surgery to reconnect their small intestine and colon. They will measure how well the intestine absorbs food and analyze stool samples to see if changes in gut bacteria are linked to better absorption.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 15 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Diagnosis of short bowel syndrome with a jejunostomy and a plan to restore jejuno-colic continuity within 3 months * Remaining post-duodenal small intestine (after the ligament of Treitz) \< 200 cm * Remaining colon \> 14% * Remaining small intestine and colon are healthy (no residual inflammatory, post-radiation, or ischemic disease) * Patient enrolled in a social security system or entitled to coverage Exclusion Criteria: * Pregnancy * Patient unable to provide consent: * Due to a disability preventing consent * Does not understand French * Patient deprived of liberty, or under legal protection (guardianship or curatorship) * Participation in another interventional study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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