Smartphone app aims to land blood pressure safely
NCT ID NCT03612271
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a mobile health system called mGlide that helps patients with uncontrolled high blood pressure monitor their BP at home and automatically share readings with their healthcare team. The system alerts doctors when BP goes off track, allowing for timely medication adjustments. The trial includes 395 participants, including stroke survivors and others at high risk for heart disease, from clinics serving low-income and minority communities.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- mGlide mobile health system (behavioral intervention using wireless BP monitor and smartphone)
- What this could lead to
- If successful, this could provide a practical, scalable way to improve blood pressure control in high-risk patients, especially in underserved communities.
- What could go wrong
- This is a relatively small trial (395 participants) testing a behavioral intervention, not a new drug. Results may not apply to all populations or settings, and long-term adherence to self-monitoring is uncertain.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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395 people
The number who actually took part.
- Started
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Mar 2019
- Expected to finish
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Apr 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Stroke survivors (ischemic stroke or intra-parenchymal hemorrhage) or patients who have not had a stroke but carry a high risk of stroke or cardiovascular disease (CVD) events (\>7.5% over 10 years) as defined by the AHA/ACC guideline on risk stratification9 * Diagnosis of uncontrolled HTN at the time of study enrollment (need not have stroke) * Uncontrolled blood pressure (BP) defined as SBP \> 150 mm Hg at the last 2 clinic visits in the 6 months prior to the screening date. Alternatively, if a patient was discharged from the hospital in the 6 months prior to screening and does not have 2 clinic visits after hospital discharge, at least one hospital SBP in the last 2 days of the hospital stay must be \>150 mm Hg. Screening of uncontrolled HTN will be based on Electronic Medical Record (EMR) BP data. * Capable and willing to comply with the entire study protocol * Able to give voluntary written informed consent * English, Spanish or Hmong speaking * Have a smart phone or mobile technology device (e.g. ipad) that can transmit BP from the BP monitor. iOS and Android Compatible. (iOS 7 or higher: iPhone 4 or higher, iPod touch 5th generation or higher, iPad 2nd generation or higher. Android 4.0 or higher.) Exclusion Criteria: * Unable or unwilling to give consent * Any severe co-morbid illness including end stage kidney disease (ESRD), end stage liver disease (ESLD) or when life expectancy is less than 1 year or if primary care provider feels that medical complexity of the patient precludes clinical trial participation * Unable to complete study tasks * Any serious psychiatric illness that, in the opinion of the investigator, would interfere with subject treatment, assessment or compliance including significant delusional disorders such as schizophrenia and bipolar illness. * Do not speak English, Spanish or Hmong
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Epidemiology Clinical Research Center
Minneapolis, Minnesota, 55415, United States
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Other studies related to the condition(s) this trial covers.
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