Head-to-Head drug battle for a hidden hormone disorder

This study aims to find out which of two existing drugs, metyrapone or osilodrostat, works better and is safer for adults with a condition where the adrenal glands make too much cortisol on their own. The trial will enroll 150 people and compare how well the drugs lower cortisol levels and improve related health issues like blood pressure, weight, and blood sugar over 6 months. This is a Phase 4 study, meaning researchers are comparing these already-approved treatments in a real-world setting.