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Could a common ADHD drug boost brain function in schizophrenia?

NCT ID NCT05414058

First seen Jan 11, 2026 · Last updated Jun 10, 2026 · Updated 15 times

Summary

This study tested whether adding a long-acting stimulant (methylphenidate) to standard antipsychotic medication can improve thinking, memory, and daily functioning in people with schizophrenia or schizoaffective disorder. 35 stable adults took the drug in addition to their usual treatment. The goal was to see if it helps with symptoms like low motivation and trouble concentrating, while monitoring for any worsening of psychosis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Royal Ottawa Mental Health Centre

    Ottawa, Ontario, K1Z 7K4, Canada

Conditions

The condition(s) this trial relates to.

Psychotic Disorders schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.