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Blue blood wash may ease Post-Heart surgery complications

NCT ID NCT07212842

Disease control Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new method to reduce fluid buildup and inflammation in 124 adults having heart surgery with a heart-lung machine. The method involves washing the blood with methylene blue during a filtering process. Researchers measured fluid levels and inflammation markers before, during, and after surgery to see if this approach helps patients recover better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

124 people

The number who actually took part.

Started

Apr 2021

Finished

Mar 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Clinical diagnosis of cardiac disease requiring surgery with cardiopulmonary bypass (CPB) Age ≥ 18 years Ability to provide informed consent Exclusion Criteria: Chronic renal failure Recent cardiac catheterization within the past month Planned cardiac surgeries with an estimated CPB time of less than 60 minutes Aortic surgery Significantly impaired hepatic function

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aortic valve surgery Cardiopulmonary bypass surgery Mitral valve surgery Myocardial revascularization surgery with extracorporeal circulation

Contacts and locations

Locations

  • University of São Paulo Medical School in Ribeirão Preto

    Ribeirão Preto, São Paulo, 14049-900, Brazil

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