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Psoriasis combo therapy falls short: methotrexate trial halted

NCT ID NCT02829424

First seen Nov 20, 2025 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study looked at whether adding low-dose methotrexate to standard anti-TNF drugs could improve and prolong skin clearing in adults with moderate to severe psoriasis. About 78 participants were planned, but the trial was stopped early. The goal was to see if the combination reduced the chance of losing treatment response over two years.

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Contacts and locations

Locations

  • Assistance Publique Hôpitaux de Marseille

    Marseille, 13385, France

Conditions

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